Risch HA. Etiology of pancreatic cancer, with a hypothesis concerning the role of N-nitroso compounds and excess gastric acidity. J Natl Cancer Inst. Meat and fat intake as risk factors for pancreatic cancer: the multiethnic cohort study. Risk of pancreatic cancer in relation to alcohol drinking, coffee consumption and medical history: findings from the Japan collaborative cohort study for evaluation of cancer risk. Pancreatitis and the risk of pancreatic cancer.
International Pancreatitis Study Group. Cowgill SM, Muscarella P. The genetics of pancreatic cancer.
Am J Surg. Whitcomb DC. Genetics and alcohol: a lethal combination in pancreatic disease?. Alcohol Clin Exp Res. Mintziras I, Bartsch DK. Progress report: familial pancreatic cancer. Fam Cancer. Molecular biology of exocrine pancreatic cancer. Clin Transl Oncol. May Molecular genetics of exocrine pancreatic neoplasms. Surg Clin North Am. Molecular characterization of pancreatic neoplasms. Adv Anat Pathol. Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas.
Cancer Res. Molecular analysis to detect pancreatic ductal adenocarcinoma in high-risk groups. June Inactivation of Smad4 accelerates Kras G12D -mediated pancreatic neoplasia. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.
Distant metastasis occurs late during the genetic evolution of pancreatic cancer. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Management of pancreatic endocrine tumors in multiple endocrine neoplasia type 1.
World J Surg. Extra-intestinal manifestations of familial adenomatous polyposis. Ann Surg Oncol. Cancer facts and figures for African Americans Cancer Epidemiol Biomarkers Prev. World J Oncol. NARCA: A novel prognostic scoring system using neutrophil-albumin ratio and Ca to predict overall survival in palliative pancreatic cancer.
J Surg Oncol. Suicide in patients with pancreatic cancer. ASCO update of recommendations for the use of tumor markers in gastrointestinal cancer. Preoperative serum carcinoembryonic antigen and carbohydrate antigen levels for the evaluation of curability and resectability in patients with pancreatic adenocarcinoma. J Hepatobiliary Pancreat Surg. The use of adjusted preoperative CA to predict the recurrence of resectable pancreatic cancer.
J Surg Res. Multidetector CT angiography of pancreatic carcinoma: part I, evaluation of arterial involvement.
Adenocarcinoma of the pancreas: CT imaging. Radiol Clin North Am. Ann Surg.
Needle biopsy for suspicious lesions of the head of the pancreas: pitfalls and implications for therapy. J Gastrointest Surg. Gastrointest Endosc. Louden K. New risk factors proposed for pancreatic cancer. September 26, Neuroendocrine Tumors, v. Accessed: October 21, Tumor-node-metastasis staging of pancreatic adenocarcinoma.
CA Cancer J Clin. Staging laparoscopy with laparoscopic ultrasonography: optimizing resectability in hepatobiliary and pancreatic malignancy. J Am Coll Surg. Utility of staging laparoscopy in subsets of peripancreatic and biliary malignancies. A prospective analysis of staging laparoscopy in patients with primary and secondary hepatobiliary malignancies. Vascular resection and reconstruction for pancreatic malignancy: a single center survival study.
Systematic review of innovative ablative therapies for the treatment of locally advanced pancreatic cancer. Br J Surg. A randomized double-blind, placebo P controlled, multicenter phase III trial to evaluate the efficacy and safety of adding bevacizumab B to erlotinib E and gemcitabine G in patients pts with metastatic pancreatic cancer. A randomized phase III study of gemcitabine in combination with radiation therapy versus gemcitabine alone in patients with localized, unresectable pancreatic cancer:E Phase III randomized comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer.
Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy NAPOLI-1 : a global, randomised, open-label, phase 3 trial. Pancreatic cancer. Adjuvant combined radiation and chemotherapy following curative resection. Arch Surg. A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer.
Survival effects of adjuvant chemoradiotherapy after resection for pancreatic carcinoma. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. Cell Physiol Biochem. Rapid-fractionation preoperative chemoradiation, pancreaticoduodenectomy, and intraoperative radiation therapy for resectable pancreatic adenocarcinoma. Preoperative paclitaxel and concurrent rapid-fractionation radiation for resectable pancreatic adenocarcinoma: toxicities, histologic response rates, and event-free outcome.
March 23, ; Accessed: September 10, JAMA Surg. Boggs W. Accessed: December 22, Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an eastern cooperative oncology group trial. Perioperative mortality for pancreatectomy: a national perspective. Preoperative biliary drainage for cancer of the head of the pancreas. Correlation between preoperative biliary drainage, bile duct contamination, and postoperative outcomes for pancreatic surgery. Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer.
Prognostic significance of pathologic nodal status in patients with resected pancreatic cancer. Distal Pancreatectomy. Von Hoff, Evans, Hruban. Pancreatic Cancer. Sudbury, Mass: Jones and Bartlett; Is there still a role for total pancreatectomy?. Preventive Services Task Force.
Clinical Summary: Pancreatic Cancer: Screening. Clinical importance of delays in the initiation of appropriate antibiotic treatment for ventilator-associated pneumonia. Empirical antimicrobial therapy of septic shock patients: adequacy and impact on the outcome.
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Does beta-lactam pharmacokinetic variability in critically ill patients justify therapeutic drug monitoring? A Systematic Review. Ann Intensive Care. Pharmacokinetics-pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients.
Crit Care. GRADE guidelines: 2.
Framing the question and deciding on important outcomes. J Clin Epidemiol. The effect of pathophysiology on pharmacokinetics in the critically ill patient--concepts appraised by the example of antimicrobial agents.